منابع مشابه
Biochemistry of Some Peptide and Steroid Antibiotics
and the level of ATP in platelets. The possibility exists that ATP may represent one of the anchoring sites for 5-HT in the body. At present, it seems most appropriate to look upon 5-HT in platelets as a transportation form of the amine, since in this locus, unlike most of the other sites in which 5-HT is found in high concentration, enzymes concerned with the formation of the amine are not pre...
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Biochemists and geneticists, represented by Doug and Bill in classic essays, have long debated the merits of their methods. We revisited this issue using genomic data from the budding yeast, Saccharomyces cerevisiae, and found that genetic interactions outperformed protein interactions in predicting functional relationships between genes. However, when combined, these interaction types yielded ...
متن کاملGLUCAGON-LIKE PEPTIDE 1: BIOChEMISTRy, SECRETION AND MAIN PhySIOLOGICAL EFFECTS
the peptide hormone glucagon-like peptide 1 (glp-1), produced in the intestinal l-cells by differential processing of proglucagon, is secreted in response to meal intake. glp-1 affects various systems, the gastrointestinal and pancreatic systems being the best studied, either by direct binding to the glp-1 receptor, at the target-cells surface, or indirectly as a result of paracrine regulation....
متن کاملSaccharide‐Containing Dynamic Proteoids
Dynamic proteoids are dynamic covalent analogues of proteins, which can be used as new adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dial...
متن کاملSaccharide-RNA recognition.
Among saccharides, the antibiotics of the aminoglycoside family are the best-studied class of molecules interacting with RNA. By binding to RNA targets, aminoglycosides act as inhibitors of protein biosynthesis, they interfere with protein-RNA interaction of retroviral regulatory elements, and they inhibit the catalytic action of ribozymes. Here, we survey the available data on molecular struct...
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ژورنال
عنوان ژورنال: Science
سال: 2002
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.297.5579.161b